Interactions
An Overview of Carisoprodol Interactions
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Carisoprodol (Soma®) can potentially interact with several other medications. Some of these medicines that may lead to carisoprodol drug interactions include:
- Alcohol
- Armodafinil (Nuvigil™)
- Barbiturates, including:
-
- Amobarbital (Amytal®)
- Butalbital (Fioricet®, Fiorinal®)
- Pentobarbital (Nembutal®)
- Phenobarbital (Luminal®)
- Secobarbital (Seconal®)
- Benzodiazepines, including:
-
- Alprazolam (Xanax®, Xanax® XR)
- Chlordiazepoxide (Librium®, Limbitrol®, Librax®)
- Clonazepam (Klonopin®)
- Clorazepate (Tranxene®)
- Diazepam (Valium®)
- Estazolam (ProSom®)
- Flurazepam (Dalmane®)
- Lorazepam (Ativan®)
- Midazolam (Versed®)
- Temazepam (Restoril®)
- Triazolam (Halcion®)
- Carbamazepine (Carbatrol®, Epitol®, Equetro®, Tegretol®)
- Certain antibiotics or antifungal medications, including:
-
- Fluconazole (Diflucan®)
- Ketoconazole (Nizoral®)
- Miconazole
- Isoniazid
- Rifampin (Rifadin®)
- Certain antidepressants, including:
-
- Fluoxetine (Prozac®, Sarafem®)
- Fluvoxamine (Luvox®, Luvox® CR)
- Sertraline (Zoloft®)
- Tranylcypromine (Parnate®)
- Certain proton pump inhibitors (PPIs), including:
-
- Esomeprazole (Nexium®)
- Lansoprazole (Prevacid®)
- Omeprazole (Prilosec®)
- Rabeprazole (AcipHex®)
- Delavirdine (Rescriptor®)
- Gemfibrozil (Lopid®)
- Modafinil (Provigil®)
- Narcotics or opiates, such as morphine, oxycodone (OxyContin®), or hydrocodone (Lortab®, Vicodin®)
- Phenytoin (Dilantin®, Phenytek®)
- Sleep medications
- Ticlopidine (Ticlid®).
Narcotics or Opiates
Combining an opiate or narcotic with carisoprodol can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk to your healthcare provider before taking carisoprodol with an opiate or narcotic.
Phenytoin (Dilantin, Phenytek)
The liver metabolizes carisoprodol into meprobamate, a different drug with anti-anxiety properties. Phenytoin increases this process, decreasing the level of carisoprodol and increasing the level of meprobamate in the blood. It is not known how this interaction might change the effectiveness or side effects of carisoprodol.
Ticlopidine (Ticlid)
The liver metabolizes carisoprodol into meprobamate, a different drug with anti-anxiety properties. Ticlopidine inhibits this process, increasing the level of carisoprodol and decreasing the level of meprobamate in the blood. It is not known how this interaction might change the effectiveness or side effects of carisoprodol.
Sleep Medications
Combining a sleep medication with carisoprodol can increase your risk of side effects, such as drowsiness, confusion, memory loss, or difficulty breathing. Serious side effects may occur. Make sure to talk to your healthcare provider before taking carisoprodol with a sleep medication.
It is possible that not all carisoprodol drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions with carisoprodol that may apply to you.